Killing cancers with Z-DNA: A new approach to treating therapy resistant tumors that targets a very-specific cell-death pathway - EurekAlert
From basic science to a new treatment modality. The left-handed Z-DNA conformation was dismissed as biologically irrelevant despite strong biochemical and genetic evidence supporting a role for this alternative conformation in regulating immune responses. The…
image: A small molecule induces Z-DNA formation in tumors to activate an inflammatory cell-death pathway that is expressed in the cells supporting growth of the cancer cell. The resulting immune resp… [+4740 chars]
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