
A long-acting formulation of rifabutin is effective for prevention and treatment of Mycobacterium tuberculosis - Nature.com

Non-adherence to anti-tubercular therapy Mycobacterium tuberculosis infection can lead to treatment failure and even the development of drug resistance. In this work, the authors develop a long-acting delivery system of the anti-tuberculosis drug rifabutin an…
Amphiphilic additives enhance RFB solubility and improve LA-RFB release kinetics
LA-RFB formulations were prepared by dissolving RFB at the maximum solubility in DMSO or NMP (202±22 and 148±34mgmL1,… [+30334 chars]
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